Targeted Therapy in Nonmelanoma Skin Cancers
نویسندگان
چکیده
منابع مشابه
Targeted Therapy in Nonmelanoma Skin Cancers
Nonmelanoma skin cancer (NMSC) is the most prevalent cancer in light-skinned populations, and includes mainly Basal Cell Carcinomas (BCC), representing around 75% of NMSC and Squamous Cell Carcinomas (SCC). The incidence of these tumors is continuously growing. It was found that the overall number of procedures for NMSC in US rose by 76%, from 1,158,298 in 1992 to 2,048,517 in 2006. Although mo...
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Photodynamic therapy involves the use of light to activate a photosensitizer, localized in the diseased skin, resulting in the formation of cytotoxic reactive oxygen species. Topical photodynamic therapy (PDT) is used to treat nonmelanoma skin cancers, such as actinic keratoses, Bowen's disease, and basal cell carcinoma, superficial as well as nodular. This article presents up-to-date, practica...
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41:3-8. (4) Partin AW, Carter HB. Chan DW. Epstein JI, Oesteriing JE, Rock RC, et al. Prostate specific antigen in the staging of localized prostate cancer: influence of tumor differentiation, tumor volume and benign hyperplasia. J Urol 1990:143:747-52. (5) Thalmann GN, Sikes RA, Chang S-M, Johnston DA, von Eschenbach AS, Chung LW. Suramin-induced decrease in prostate-specific antigen expressio...
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Photodynamic therapy (PDT) involves the administration of a photosensitizing drug and its subsequent activation by light at wavelengths matching the absorption spectrum of the photosensitizer. Because the skin is readily accessible to light-based therapies, PDT with systemic and particularly with topical agents has become important in treating cutaneous disorders. Topical PDT is indicated for t...
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Novel strategies are urgently needed to address the millions of nonmelanoma skin cancers treated in the United States annually. The need is greatest for those patients who are poor surgical candidates or those prone to numerous nonmelanoma skin cancers and therefore at risk for marked disfigurement. Traditional treatment strategies include electrosurgery with curettage, radiation therapy, cryot...
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ژورنال
عنوان ژورنال: Cancers
سال: 2011
ISSN: 2072-6694
DOI: 10.3390/cancers3022255